血小板減少症:幼若血小板比率(IPF)(2)
幼若血小板比率(immature platelet fraction:IPF)は、現在では、特発性血小板減少性紫斑病(idiopathic thrombocytopenic purpura: ITP)や再生不良性貧血、肝硬変といった血小板減少性疾患の鑑別診断、化学療法や造血細胞移植後の血小板回復予測、血小板輸血適応の判断など、種々の病態・疾患において、IPF測定の有用性が報告されています。
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19. Cremer M, Weimann A, Schmalisch G, et al: Immature platelet values indicate impaired megakaryopoietic activity in neonatal early-onset thrombocytopenia. Thromb Haemost 103:1016-21, 2010
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21. Yujiri T, Tanaka Y, Tanaka M, et al: Fluctuations in thrombopoietin, immature platelet fraction, and glycocalicin levels in a patient with cyclic thrombocytopenia. Int J Hematol 90:429-30, 2009
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23. 柴山正美, 杉森尚美, 上地幸平, et al: 骨髄異形成症候群の幼若血小板高比率は7番染色体異常を含む予後不良染色体異常の存在を示唆する. 日本検査血液学会雑誌 9:136-42, 2008
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投稿者:血液内科・呼吸器内科at 01:55| 出血性疾患